TY - BOOK AU - McDonald,Roger B. TI - Biology of aging SN - 9780815345671 PY - 2019/// CY - Boca Raton : PB - CRC Press/Taylor & Francis, KW - Aging KW - Physiology KW - Cellular senescence KW - Longevity N1 - Includes bibliographical references and index; Basic concepts in the biology of aging -- Measuring biological aging -- Evolutionary theories of longevity and aging -- Cellular aging -- Genetics of longevity -- Plant senescence -- Human longevity and life span -- Common functional loss associated with aging -- Common time-dependent disease in humans -- Modulating human aging and longevity -- The implications of an extended healthspan -- Appendix: US life table calculations N2 - Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanism underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material ER -